Library of articles and research
Effect of Cilastatin on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy.
Zaballos M, Power M, Canal-Alonso MI, González-Nicolás MÁ, Vasquez-Jimenez W, Lozano-Lominchar P, Cabrerizo-Torrente P, Palencia-García N, Gago-Quiroga S, Ginel-Feito MD, Jiménez C, Lázaro A, González-Bayón L. Int J Mol Sci. 2021; 22(3):1239.
Cilastatin: a potential treatment strategy against COVID-19 that may decrease viral replication and protect from the cytokine storm.
González-Nicolás MÁ, González-Guerrero C, Pérez-Fernández VA, Lázaro A. Clin Kidney J. 2020; 13(5):903-905.
Nephroprotective Effect of Cilastatin against Gentamicin-Induced Renal Injury In Vitro and In Vivo without Altering Its Bactericidal. Efficiency.
Jado JC, Humanes B, González-Nicolás MA, Camaño S, Lara JM, Lopez B, Cercenado E, García-Bordas J, Tejedor A, Lazaro A. Antioxidants (Basel). 2020; 9(9):821.
Urinary excretion of parathyroid hormone-related protein correlates with renal function in control rats and rats with cisplatin nephrotoxicity.
Ortega A, Olea-Herrero N, Arenas MI, Vélez-Vélez E, Moreno-Gómez-Toledano R, Muñoz-Moreno C, Lázaro A, Esbrit P, Tejedor A, Bosch RJ. Am J Physiol Renal Physiol. 2019;317(4): F874-F880.
Lipid imaging for visualizing cilastatin amelioration of cisplatin-induced nephrotoxicity.
Moreno-Gordaliza E, Esteban-Fernández D, Lázaro A, Aboulmagd S, Humanes B, Tejedor A, Linscheid MW, Gómez-Gómez MM. J Lipid Res. 2018;59(9):1561-1574.
Cisplatin-induced renal inflammation is amelioreated by cilastatin nephroprotection.
Humanes B, Camaño S, Lara JM, Sabbisetti V, Gonzalez-Nicolás MA, Bonventre JV, Tejedor A, Lazaro A. Nephrol Dial Transplant 2017; 32(10):1645-16552016.
Protective effects of cilastatin against vancomycin-induced nephrotoxicity.
Blanca Humanes, Juan Carlos Jado, Sonia Camaño, Virginia Lopez-Parra, Ana María Torres, Luis Antonio Álvarez-Sala, Emilia Cercenado, Alberto Tejedor, Alberto Lázaro. BioMed Research International, vol. 2015, Article ID 704382, 12 pages, 2015.
Reply to “Cisplatin nephrotoxicity may be sex-related".
Lázaro A, Humanes B, Jado JC, Tejedor A. Kidney Int. 2013; 83(6):1201-2.
Cilastatin protects against cisplatin-induced nephrotoxicity without compromising its anticancer efficiency in rats.
Lazaro A, Humanes B, Camano S, Moreno-Gordaliza E, Lazaro JA, Blanco-Codesido M, Lara JM, Ortiz A, Gomez-Gomez MM, Martin-Vasallo P, Tejedor A. Kidney International, 2012; 82(6):652-63.
Novel strategies in drug-induced acute kidney injury in Pharmacology.
Alberto Lazaro, Sonia Camaño, Blanca Humanes, Alberto Tejedor. Published in “Pharmacology”, edited by Luca Gallelli; Intech, Rijeka, Croatia 2012, pp. 381-396
Elemental bioimaging in kidney by LA-ICP-MS as a tool to study nephrotoxicity and renal protective strategies in cisplatin therapies.
Moreno-Gordaliza E, Giesen C, Lazaro A, Esteban-Fernández D, Humanes B, Cañas B, Panne U, Tejedor A, Jakubowski N, Gomez-Gomez MM. Anal Chem. 2011, 83(20): 7933-40.
Cilastatin attenuates cisplatin-induced proximal tubular cell damage.
Lazaro A, Camano S, Moreno-Gordaliza E, Torres AM, de Lucas C, Humanes B, Lazaro JÁ, Gómez-Gomez MM, Bosca L, Tejedor A. J Pharmacol Exp Ther. 2010, 334 (2): 419-429.
Cilastatin protection against cyclosporin A-induced nephrotoxicity: clinical evidence.
Tejedor A, Torres AM, Castilla M, Lazaro JA, de Lucas C, Caramelo C. Curr Med Res Opin. 2007 Mar;23(3):505-13.
Inhibition of brush border dipeptidase with cilastatin reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells.
Pérez M, Castilla M, Torres AM, Lázaro JA, Sarmiento E, Tejedor A Nephrol Dial Transplant. 2004; 19(10):2445-55.
